OS is the gold standard of endpoints but as increasing numbers of effective salvage treatments become available for many types of cancer, much larger numbers of patients are included this requires a longer follow-up period and increases the cost of clinical trials. The published Consolidated Standards of Reporting Trials (CONSORT) best-practice guidelines encourage the reporting of clearly defined primary and secondary outcome measures. The choice of endpoints in oncology trials is a major problem.

Surrogate endpoints are tumor-centered clinical endpoints that can be used as substitutes for patient-centered clinical endpoints, particularly OS.

In the treatment of cancer, endpoints can be classified into two categories: 'patient-centered clinical endpoints' including overall survival (OS) and health-related quality of life (QoL), and 'tumor-centered clinical endpoints' such as progression-free survival. The job of a SAS Programmer can be a challenging and rewarding position providing opportunities for technically minded people.Endpoints are measurable clinical and biological findings that are used for the development and assessment of treatment options. If this sounds like you why not consider a career within the Drug Development sector where you can contribute to the improvement of people’s health worldwide. We conducted an interview with a Lead SAS Programmer working within the pharmaceutical industry. We wanted to know what life is like working in a SAS Programming job, what a typical day involves, how did start this career and where can this career lead you? Take a look at their response here:Īs a SAS programmer in the pharma sector, we provide statistical programming support for the statisticians and statistical programming expertise for the company. We write programs to create statistical tables, listings, and graphs. Independently QC peer programmers’ statistical tables, listings, and graphs. Write programs to create the analysis database, meet milestones, provide functional guidance and develop operating procedures. What is a typical day for a SAS Programmer involve?Īs a SAS programmer, we would typically work on the development of SAS code, that creates analysis datasets, tables, figures, listings, electronic submission packages, to be included in Clinical Summary Reports submissions to the health authorities such as the FDA. I did a Maths and Biology degree, followed by a Computer Science postgraduate. What do you enjoy most about your job as a SAS Programmer ? I took a graduate position within a Clinical Contract Research Organisation, and my role as a SAS programmer evolved from there. I enjoy being part of a local and global team environment. I enjoy being a part of the drug development life cycle and it is rewarding to see a drug that I have worked on becoming available on the market.

Oncology sas interview questions